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Showing posts from March, 2026

Coagulation and Bleeding Disorders

  Bleeding is one of the most primal responses of the human body to injury. In most cases, it stops on its own within minutes, thanks to a tightly controlled biological process called haemostasis. But when haemostasis fails — whether because a vessel bleeds too much, too long, or clots too easily — the consequences can range from uncomfortable bruising to life-threatening haemorrhage. The medical laboratory is at the heart of diagnosing and monitoring bleeding and clotting disorders. Through a carefully selected panel of tests, clinical scientists can pinpoint exactly where the haemostatic system has broken down and guide clinicians toward the right treatment. In this post, we take a deep dive into the science of coagulation, the most common disorders associated with it, and the laboratory tests that help us understand them. 1. Haemostasis: The Body's Clotting System Haemostasis is the process by which bleeding stops after injury. It involves three overlapping phases that work toge...

Inside the Medical Laboratory: The People, Roles, and Daily Realities of a Career in Clinical Lab Science

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  Seventy percent of clinical decisions depend on laboratory data. That statistic is cited often — but what’s rarely cited is who generates that data. The medical laboratory sits at the intersection of science, technology, clinical medicine, and patient care, staffed by professionals who are highly trained, deeply competent, and almost entirely invisible to the people whose lives they help save. This is their story. Who Works in the Lab? The terminology varies by country, but the core roles are consistent. Medical Laboratory Scientists (MLS) / Biomedical Scientists (BMS)  are the backbone of the laboratory workforce. They hold university degrees in medical laboratory science or biomedical science, followed by supervised practical training and professional registration. They perform, interpret, and authorize the full range of laboratory testing. Medical Laboratory Technicians (MLT)  work under the supervision of scientists, typically with diploma-level qualifications, perf...

How Malaria Is Diagnosed in the Laboratory: A Guide to Blood Films, RDTs, and PCR

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Malaria Diagnosis: The Test That Cannot Afford to Be Wrong In sub-Saharan Africa, malaria is not an abstract concept. It is not a disease you read about in textbooks or see in travel advisories. It is a  child with a spiking fever at 2 a.m.  , limbs shaking, mother counting breaths. It is a  pregnant woman with anemia that won't respond to iron  , her body fighting an invisible parasite that threatens both her and her unborn child. It is a  returning traveler whose symptoms look deceptively like influenza  — until they don't. And in every one of these scenarios,  accurate laboratory diagnosis  is the difference between the right treatment and a dangerous guess. Treat too late, and falciparum malaria can kill in hours. Treat without testing, and you waste scarce antimalarials, delay treatment for bacterial infections, and accelerate drug resistance. Treat the wrong species, and you miss the dormant liver stage that will cause relapse months later. ...